:root {
  --ink: #172a33;
  --muted: #52666f;
  --line: #ccd6da;
  --blue: #2d5fa8;
  --blue-soft: #f1f4f9;
  --green: #26765e;
  --green-soft: #eef6f2;
  --purple: #6e52a3;
  --purple-soft: #f4f1f8;
  --amber: #a9650e;
  --amber-soft: #fbf6ec;
  --red: #b53b31;
  --red-soft: #fbefed;
}

* { box-sizing: border-box; }
html { min-width: 320px; background: #edf1f1; }
body { min-height: 100vh; margin: 0; color: var(--ink); background: #f7f8f7; font-family: Inter, ui-sans-serif, -apple-system, BlinkMacSystemFont, "Segoe UI", Arial, sans-serif; }
button, a { font: inherit; }
.skip-link { position: fixed; z-index: 20; top: 8px; left: 8px; transform: translateY(-150%); padding: 9px 12px; background: #fff; color: var(--blue); }
.skip-link:focus { transform: none; }

.practice-header { display: grid; grid-template-columns: 1fr auto; gap: 28px; align-items: end; padding: clamp(24px, 3.2vw, 48px) clamp(24px, 4.3vw, 68px) clamp(22px, 2.7vw, 38px); border-top: 5px solid; border-image: linear-gradient(90deg, var(--green), var(--blue)) 1; border-bottom: 1px solid var(--line); background: linear-gradient(90deg, #f5faf7, #f4f7fb); }
.practice-header p { margin: 0 0 9px; color: var(--green); font-size: 12px; font-weight: 800; letter-spacing: .11em; text-transform: uppercase; }
.practice-header h1 { margin: 0; font-size: clamp(34px, 4vw, 58px); font-weight: 670; letter-spacing: -.045em; line-height: 1; }
.practice-header span { display: block; max-width: 860px; margin-top: 12px; color: var(--muted); font-size: clamp(15px, 1.2vw, 19px); line-height: 1.4; }
.practice-header-actions { display: flex; flex-wrap: wrap; justify-content: flex-end; gap: 9px; align-self: center; }
.practice-header-actions a { padding: 11px 15px; border: 1px solid var(--blue); background: #fff; color: var(--blue); font-size: 14px; font-weight: 750; text-decoration: none; }
.practice-header-actions a:first-child { background: var(--blue); color: #fff; }
.practice-header-actions a:hover, .practice-header-actions a:focus-visible { background: var(--ink); border-color: var(--ink); color: #fff; outline: 0; }

.practice-shell { display: grid; grid-template-columns: minmax(235px, 290px) minmax(0, 1fr); gap: clamp(24px, 3vw, 44px); width: min(1540px, 100%); min-height: 690px; margin: 0 auto; padding: clamp(24px, 3vw, 44px) clamp(24px, 4.3vw, 68px); }
.case-sidebar { display: grid; align-content: start; gap: 17px; }
.case-sidebar-heading span, .section-label span, .case-heading p, .case-progress-row span { color: var(--blue); font-size: 10px; font-weight: 800; letter-spacing: .1em; line-height: 1.2; text-transform: uppercase; }
.case-sidebar-heading strong { display: block; margin-top: 5px; font-size: 18px; line-height: 1.2; }
.case-nav { display: grid; border-top: 2px solid var(--ink); }
.case-nav button { display: grid; grid-template-columns: 32px minmax(0, 1fr); gap: 10px; align-items: center; min-height: 64px; padding: 10px 9px; border: 0; border-bottom: 1px solid var(--line); background: transparent; color: var(--muted); text-align: left; cursor: pointer; }
.case-nav button:hover, .case-nav button:focus-visible { background: #fff; color: var(--ink); outline: 2px solid var(--blue); outline-offset: -2px; }
.case-nav button[aria-current="true"] { border-left: 5px solid var(--blue); background: var(--blue-soft); color: var(--ink); }
.case-nav button.is-complete { border-left-color: var(--green); }
.case-nav b { display: grid; place-items: center; width: 28px; height: 28px; border-radius: 50%; background: #dce4e8; color: #536871; font-size: 11px; }
.case-nav button[aria-current="true"] b { background: var(--blue); color: #fff; }
.case-nav button.is-complete b { background: var(--green); color: #fff; }
.case-nav strong { font-size: 13px; line-height: 1.25; }
.case-disclaimer { margin: 0; padding: 13px 14px; border-left: 4px solid var(--amber); background: var(--amber-soft); color: #695b46; font-size: 12px; line-height: 1.4; }

.case-workspace { display: grid; grid-template-rows: auto auto minmax(0, 1fr) auto; min-width: 0; border-top: 4px solid var(--blue); background: #fff; box-shadow: 0 18px 45px rgba(31, 50, 59, .08); }
.case-progress-row { display: grid; grid-template-columns: auto minmax(160px, 320px); gap: 28px; align-items: center; padding: 14px 22px; border-bottom: 1px solid var(--line); background: #fafbfb; }
.case-progress-row strong { display: block; margin-top: 4px; color: var(--ink); font-size: 13px; }
.case-progress { height: 7px; overflow: hidden; background: #dbe3e6; }
.case-progress i { display: block; height: 100%; width: 0; background: linear-gradient(90deg, var(--green), var(--blue)); transition: width .25s ease; }
.case-heading { padding: clamp(18px, 2.2vw, 30px) clamp(22px, 2.8vw, 38px) 14px; }
.case-heading p { margin: 0 0 7px; color: var(--green); }
.case-heading h2 { margin: 0; font-size: clamp(26px, 2.5vw, 39px); font-weight: 650; letter-spacing: -.035em; line-height: 1.08; }

.case-study-layout { display: grid; grid-template-columns: minmax(310px, .85fr) minmax(0, 1.35fr); min-height: 0; border-top: 1px solid var(--line); }
.case-study-layout.is-complete { grid-template-columns: 1fr; }
.case-facts, .case-question { min-width: 0; }
.case-facts { display: grid; grid-template-rows: auto minmax(0, 1fr); border-right: 1px solid var(--line); background: var(--blue-soft); }
.section-label { display: grid; grid-template-columns: 1fr auto; align-items: center; gap: 15px; padding: 12px 18px; border-bottom: 1px solid var(--line); background: rgba(255,255,255,.66); }
.section-label strong { color: #65767d; font-size: 11px; }
.facts-list { display: grid; align-content: stretch; min-height: 0; }
.fact-row { display: grid; align-content: center; min-height: 88px; padding: 13px 19px; border-bottom: 1px solid #d3dce7; }
.fact-row:last-child { border-bottom: 0; }
.fact-row span { color: #63767f; font-size: 9px; font-weight: 800; letter-spacing: .09em; text-transform: uppercase; }
.fact-row strong { display: block; margin-top: 5px; color: var(--ink); font-size: clamp(15px, 1.15vw, 18px); line-height: 1.18; }
.fact-row p { margin: 5px 0 0; color: var(--muted); font-size: 13px; line-height: 1.34; }

.case-question { display: grid; grid-template-rows: auto auto auto minmax(0, 1fr) auto; align-content: start; }
.case-question h3 { margin: clamp(19px, 2.2vw, 30px) clamp(22px, 2.7vw, 36px) 7px; font-size: clamp(23px, 2vw, 32px); font-weight: 650; letter-spacing: -.025em; line-height: 1.12; }
.case-question > p { margin: 0 clamp(22px, 2.7vw, 36px); color: var(--muted); font-size: 14px; line-height: 1.38; }
.answer-options { display: grid; align-content: center; gap: 10px; padding: clamp(18px, 2.1vw, 28px) clamp(22px, 2.7vw, 36px); }
.answer-option { display: grid; grid-template-columns: 42px minmax(0, 1fr); align-items: center; min-height: 58px; padding: 0; border: 1px solid #cbd5d9; background: #fff; color: var(--ink); text-align: left; cursor: pointer; }
.answer-option:hover, .answer-option:focus-visible { border-color: var(--blue); outline: 2px solid rgba(45,95,168,.18); outline-offset: 1px; }
.answer-option b { display: grid; place-items: center; align-self: stretch; border-right: 1px solid #cbd5d9; color: var(--purple); font-size: 14px; }
.answer-option span { padding: 11px 14px; font-size: clamp(14px, 1vw, 16px); font-weight: 620; line-height: 1.25; }
.answer-option.is-correct { border-color: var(--green); background: var(--green-soft); }
.answer-option.is-correct b { border-color: rgba(38,118,94,.28); color: var(--green); }
.answer-option.is-incorrect { border-color: var(--red); background: var(--red-soft); }
.answer-option.is-incorrect b { border-color: rgba(181,59,49,.28); color: var(--red); }
.answer-option:disabled { cursor: default; opacity: .74; }
.answer-option.is-correct:disabled { opacity: 1; }
.answer-feedback { margin: 0 clamp(22px, 2.7vw, 36px) clamp(18px, 2vw, 26px); padding: 13px 15px; border-left: 5px solid var(--green); background: var(--green-soft); color: #405f54; font-size: 13px; line-height: 1.4; }
.answer-feedback.is-incorrect { border-left-color: var(--red); background: var(--red-soft); color: #694b46; }
.answer-feedback strong { display: block; margin-bottom: 4px; color: var(--ink); font-size: 14px; }

.answer-options.is-checklist { align-content: start; }
.test-checklist { display: grid; gap: 12px; }
.checklist-instruction { margin: 0; color: var(--muted); font-size: 12px; line-height: 1.35; }
.checklist-instruction strong { color: var(--ink); }
.checklist-grid { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 8px; }
.checklist-item { display: grid; grid-template-columns: 27px minmax(0, 1fr); gap: 10px; align-items: center; min-height: 52px; padding: 9px 11px; border: 1px solid #cbd5d9; background: #fff; color: var(--ink); text-align: left; cursor: pointer; }
.checklist-item:hover, .checklist-item:focus-visible { border-color: var(--blue); outline: 2px solid rgba(45,95,168,.18); outline-offset: 1px; }
.checklist-item > span:last-child { font-size: 13px; font-weight: 650; line-height: 1.22; }
.checklist-box { display: grid; place-items: center; width: 22px; height: 22px; border: 2px solid #aab7bc; background: #fff; color: transparent; font-size: 13px; font-weight: 900; }
.checklist-item.is-selected { border-color: var(--blue); background: var(--blue-soft); }
.checklist-item.is-selected .checklist-box { border-color: var(--blue); background: var(--blue); color: #fff; }
.checklist-item.is-correct { border-color: var(--green); background: var(--green-soft); }
.checklist-item.is-correct .checklist-box { border-color: var(--green); background: var(--green); color: #fff; }
.checklist-item.is-incorrect { border-color: var(--red); background: var(--red-soft); }
.checklist-item.is-incorrect .checklist-box { border-color: var(--red); background: var(--red); color: #fff; }
.checklist-item.is-missed { border-color: var(--amber); background: var(--amber-soft); }
.checklist-item.is-missed .checklist-box { border-color: var(--amber); }
.checklist-item:disabled { cursor: default; opacity: 1; }
.checklist-submit-row { display: flex; justify-content: space-between; gap: 12px; align-items: center; padding: 10px 12px; border-left: 4px solid var(--purple); background: var(--purple-soft); color: #5f5572; font-size: 12px; }
.checklist-submit-row button { padding: 8px 12px; border: 1px solid var(--purple); background: var(--purple); color: #fff; font-size: 12px; font-weight: 750; cursor: pointer; }
.checklist-submit-row button:disabled { border-color: #b7b0c1; background: #d9d5de; color: #746d7e; cursor: not-allowed; }

.answer-options.is-narrow-list { align-content: start; padding-top: 14px; }
.narrow-list { display: grid; min-width: 0; }
.narrow-stage-strip { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 6px; }
.narrow-stage-strip > div { display: grid; grid-template-columns: 24px minmax(0, 1fr); gap: 6px; align-items: center; min-width: 0; padding: 7px; border-top: 3px solid #c5cdd1; background: #f6f7f6; color: #77848a; }
.narrow-stage-strip b { display: grid; place-items: center; width: 22px; height: 22px; border-radius: 50%; background: #a8b2b7; color: #fff; font-size: 10px; }
.narrow-stage-strip span { min-width: 0; font-size: 10px; line-height: 1.15; }
.narrow-stage-strip strong { display: block; margin-bottom: 2px; color: #65757c; font-size: 8px; letter-spacing: .06em; text-transform: uppercase; }
.narrow-stage-strip > .is-active { border-top-color: var(--purple); background: var(--purple-soft); color: #514765; }
.narrow-stage-strip > .is-active b { background: var(--purple); }
.narrow-stage-strip > .is-active strong { color: #574186; }
.narrow-stage-strip > .is-complete { border-top-color: var(--green); background: var(--green-soft); color: #42675c; }
.narrow-stage-strip > .is-complete b { background: var(--green); }
.narrow-stage-strip > .is-complete strong { color: #1f7058; }
.narrow-instruction { margin: 9px 0 0; color: #40555e; font-size: 12px; font-weight: 680; line-height: 1.3; }
.narrow-class-grid { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 10px; align-items: start; margin-top: 10px; }
.narrow-class-column, .narrow-class-group, .narrow-class-cards { display: grid; gap: 6px; min-width: 0; }
.narrow-class-column { align-content: start; gap: 8px; }
.narrow-class-heading { margin: 0; padding: 5px 8px; border-left: 4px solid var(--blue); background: #eaf0f8; color: #214f8d; font-size: 9px; font-weight: 850; letter-spacing: .08em; line-height: 1.1; text-transform: uppercase; }
.narrow-class-group[data-drug-class="Ib"] .narrow-class-heading { border-left-color: var(--purple); background: var(--purple-soft); color: #574186; }
.narrow-class-group[data-drug-class="Ic"] .narrow-class-heading { border-left-color: var(--green); background: var(--green-soft); color: #1f7058; }
.narrow-class-group[data-drug-class="III"] .narrow-class-heading { border-left-color: var(--amber); background: var(--amber-soft); color: #8c550d; }
.narrow-drug-card { display: grid; grid-template-columns: minmax(92px, .72fr) minmax(94px, .65fr); grid-template-areas: "name status" "reason reason"; gap: 3px 8px; align-content: center; min-height: 58px; padding: 8px 9px; border: 1px solid #cbd4d8; border-left: 5px solid #a8b2b7; background: #fff; color: var(--ink); font: inherit; text-align: left; cursor: pointer; }
.narrow-drug-card:hover, .narrow-drug-card:focus-visible { border-color: #87969d; outline: 2px solid rgba(45,95,168,.18); outline-offset: 1px; }
.narrow-drug-card.is-revealed { cursor: default; }
.narrow-drug-card.is-not-yet { border-left-color: #7d8b91; background: #f6f7f6; }
.narrow-drug-card > strong { grid-area: name; min-width: 0; font-size: 13px; line-height: 1.15; }
.narrow-drug-status { grid-area: status; justify-self: end; padding: 3px 5px; border: 1px solid currentColor; color: #617178; font-size: 8px; font-weight: 800; letter-spacing: .05em; line-height: 1.15; text-align: center; text-transform: uppercase; }
.narrow-drug-reason { grid-area: reason; color: #53656c; font-size: 10px; line-height: 1.22; }
.narrow-drug-reason[hidden] { display: none; }
.narrow-drug-card.is-revealed[data-status="ineffective"] { border-left-color: var(--blue); background: var(--blue-soft); }
.narrow-drug-card.is-revealed[data-status="ineffective"] .narrow-drug-status { color: #214f8d; }
.narrow-drug-card.is-revealed[data-status="contraindicated"] { border-left-color: var(--red); background: var(--red-soft); }
.narrow-drug-card.is-revealed[data-status="contraindicated"] .narrow-drug-status { color: #a13228; }
.narrow-drug-card.is-revealed[data-status="poorfit"] { border-left-color: var(--amber); background: var(--amber-soft); }
.narrow-drug-card.is-revealed[data-status="poorfit"] .narrow-drug-status { color: var(--amber); }
.narrow-drug-card.is-revealed[data-status="potential"] { border-left-color: var(--green); background: var(--green-soft); }
.narrow-drug-card.is-revealed[data-status="potential"] .narrow-drug-status { color: #1f7058; }
.narrow-drug-card.is-revealed[data-status="reserve"] { border-left-color: var(--purple); background: var(--purple-soft); }
.narrow-drug-card.is-revealed[data-status="reserve"] .narrow-drug-status { color: #574186; }
.narrow-progress { display: grid; grid-template-columns: minmax(0, 1fr) auto; gap: 10px; align-items: center; margin-top: 9px; padding: 8px 9px; border-left: 4px solid var(--purple); background: var(--purple-soft); color: #5f5572; font-size: 11px; }
.narrow-progress p { margin: 0; line-height: 1.28; }
.narrow-progress strong { color: #574186; }
.narrow-progress button { padding: 7px 9px; border: 1px solid var(--purple); background: var(--purple); color: #fff; font: inherit; font-size: 11px; font-weight: 750; cursor: pointer; }
.narrow-progress button:disabled { border-color: #b7b0c1; background: #d9d5de; color: #746d7e; cursor: not-allowed; }
.narrow-progress.is-complete { grid-template-columns: 1fr; border-left-color: var(--green); background: var(--green-soft); color: #42675c; }
.narrow-progress.is-complete strong { color: #1f7058; }

.case-controls { display: flex; justify-content: flex-end; gap: 10px; padding: 13px 18px; border-top: 1px solid var(--line); background: #fafbfb; }
.case-controls button { min-height: 40px; padding: 8px 14px; border: 1px solid #bcc9ce; background: #fff; color: #435861; font-size: 13px; font-weight: 700; cursor: pointer; }
.case-controls button:hover:not(:disabled), .case-controls button:focus-visible { border-color: var(--blue); color: var(--blue); outline: 2px solid rgba(45,95,168,.15); outline-offset: 1px; }
.case-controls button.primary { border-color: var(--blue); background: var(--blue); color: #fff; }
.case-controls button:disabled { cursor: not-allowed; opacity: .45; }

.case-complete { display: grid; align-content: center; gap: 18px; min-height: 420px; padding: clamp(28px, 4vw, 60px); }
.case-complete > span { color: var(--green); font-size: 10px; font-weight: 800; letter-spacing: .1em; text-transform: uppercase; }
.case-complete h3 { margin: 0; font-size: clamp(28px, 3vw, 44px); letter-spacing: -.035em; line-height: 1.08; }
.case-complete > p { max-width: 820px; margin: 0; color: var(--muted); font-size: 15px; line-height: 1.45; }
.case-summary { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); border-top: 1px solid var(--line); }
.case-summary div { display: grid; grid-template-columns: minmax(95px, .55fr) minmax(0, 1.45fr); gap: 18px; padding: 14px 18px 14px 0; border-right: 1px solid var(--line); border-bottom: 1px solid var(--line); }
.case-summary div:nth-child(even) { padding-right: 0; padding-left: 18px; border-right: 0; }
.case-summary b { color: var(--green); font-size: 13px; }
.case-summary p { margin: 0; color: var(--ink); font-size: 14px; line-height: 1.35; }

.practice-sources { display: flex; flex-wrap: wrap; gap: 9px 18px; padding: 18px clamp(24px, 4.3vw, 68px) 28px; border-top: 1px solid var(--line); background: #edf1f1; color: #5a6c73; font-size: 11px; line-height: 1.4; }
.practice-sources strong { color: var(--ink); }
.practice-sources a { color: var(--blue); }

@media (max-width: 900px) {
  .practice-header { grid-template-columns: 1fr; align-items: start; }
  .practice-header-actions { justify-content: flex-start; }
  .practice-shell { grid-template-columns: 1fr; padding-left: 18px; padding-right: 18px; }
  .case-nav { grid-template-columns: repeat(4, minmax(150px, 1fr)); overflow-x: auto; }
  .case-disclaimer { display: none; }
  .case-study-layout { grid-template-columns: 1fr; }
  .case-facts { border-right: 0; border-bottom: 1px solid var(--line); }
  .facts-list { grid-template-columns: repeat(2, 1fr); }
  .case-progress-row { grid-template-columns: 1fr; gap: 10px; }
}

@media (max-width: 620px) {
  .practice-header { padding: 24px 18px; }
  .practice-header h1 { font-size: 34px; }
  .facts-list { grid-template-columns: 1fr; }
  .case-summary { grid-template-columns: 1fr; }
  .case-summary div, .case-summary div:nth-child(even) { grid-template-columns: 1fr; gap: 5px; padding-right: 0; padding-left: 0; border-right: 0; }
  .case-controls { display: grid; grid-template-columns: 1fr 1fr; }
  .case-controls .primary { grid-column: 1 / -1; grid-row: 1; }
  .narrow-stage-strip { grid-template-columns: 1fr; }
  .narrow-class-grid { grid-template-columns: 1fr; }
  .narrow-progress { grid-template-columns: 1fr; }
  .narrow-progress button { justify-self: start; }
  .checklist-grid { grid-template-columns: 1fr; }
  .checklist-submit-row { align-items: stretch; flex-direction: column; }
  .checklist-submit-row button { align-self: start; }
}

@media (prefers-reduced-motion: reduce) {
  * { scroll-behavior: auto !important; transition: none !important; }
}